Description The growing interest of scientifical and pharmaceutical communities in the field of biological reactions, has led to the improvement of stopped-flow mixing system that is capable of measuring rapid kinetic reactions with a timescale in the range of 0.5 ms to minutes. The SFM-4000 stopped-flow is available for a wide range of applications, e.g …
Kinetic measurements via Stopped-Flow apparatus Leggi altro »
Description Mass photometry, an analytical technology for biomolecular characterization, measures the mass of single particles in solution. The principle behind mass photometry is simple: a single molecule in contact with a measurement surface (e.g. a coverslip), exposed to a beam of light, produces a small but measurable light scattering signal, which is directly proportional to …
Description Nuclear Magnetic Resonance (NMR) spectroscopy is a strategic tool for studying a variety biomolecular systems, providing a wealth of information at the atomic level. Using NMR, a wide range of observables, including chemical shift values, nuclear spin relaxation rates, exchange effects, and diffusion coefficients can be measured to obtain structural and dynamic details on …
Nuclear Magnetic Resonance (NMR) for biological systems Leggi altro »
Description Surface Plasmon Resonance (SPR) is a label-free, fluidics based, real-time detection technology based on analyte binding to chemically coated sensor chips. The Octet SF3 System is a fully automated, three channel, SPR-based biosensing system in a flow injection analysis configuration. The SF3 apparatus is a Surface Plasmon Resonance benchtop molecule-molecule interaction detection system, designed for high-end …
Description BioSAXS is a technique used for structural studies of proteins in their native state. BioSAXS helps identify structural states and changes of biological macromolecules and relate these changes to their functions. In fact, many diseases are related to the misfolding of biological macromolecules. Structure changes can occur as a function of time, pH, ionic …
Description A large number of proteins now emerge as important targets in the drug discovery process with the advent of the Structural Genomics and Structural Proteomics era. For this reason, the knowledge of the 3-D structure of proteins has a great potential to accelerate the rational design of novel and improved drug candidates. X-ray crystallography …
