ITACA.SB Workshop
25 - 27 February 2026 | Catania, Italy

MassSpec in Structural Biology and Beyond

This interdisciplinary workshop explores how mass spectrometry and complementary analytical approaches contribute to understanding the structure, dynamics, and function of biological systems. It brings together researchers working at the interface of structural biology, analytical sciences, and the life sciences to discuss recent methodological advances and emerging applications, ranging from biomolecular structures and interactions to complex biological processes. By extending beyond traditional disciplinary boundaries, the workshop aims to foster cross-disciplinary dialogue and highlight innovative strategies addressing current challenges across the life sciences.

Event free of charge, however the registration is mandatory.

➡️➡️➡️  REGISTRATIONS closed (for late registration please contact info@itaca-sb.it)

Venue:

CNR Area della Ricerca di Catania

Via Paolo Gaifami, 18

95126 Catania, Italy

Aula Convegni

💰💰💰Travel grants are available for early career participants (PhDs, PostDocs). Applicants should indicate on the registration form if they wish to be considered. ITACA.SB travel grants are allocated on the basis of the quality of the submitted abstract. Selection of awardees is handled directly by the organizers.

Speakers

Angela Bachi

IFOM-ETS Milan

Victoria Barygina

University of Florence – LENS

Vincenzo Cunsolo

University of Catania

Giuseppe di Natale

CNR-IC Catania

Angelo Fontana

CNR-ICB Napoli

Valentina Giglio

CNR-IPCB Catania

Roberto Marotta

IIT Genoa

Edoardo Marco Napoli

CNR-ICB Catania

Angelo Palmigiano

CNR-IPCB Catania

Giuseppe Pappalardo

CNR-IC Catania

Francesco Saverio Pavone

University of Florence – LENS

Luigi Russo

University of Campania

Laura Siracusa

CNR-ICB Catania

Programme

11:00 – 13:00 – Arrivals

13:00 – 14:00 – Lunch

14:00 – 14:15 – Welcome and Opening Remarks – Michele Saviano, Scientific Coordinator of ITACA.SB

Afternoon session 1

Chair: Danilo Milardi

14:15 – 14:45 – (Keynote) Protein characterization by mass spectrometry – from structures to interactions and mechanisms – Pietro Luigi Mauri, CNR-IEOMI

14:45 – 15:15 – (Keynote) Small Molecules and MS-based Approaches in the Immunotherapeutic Landscape – Angelo Fontana, CNR-ICB Naples

15:15 – 15:45 – Targeting Amyloid-β Misfolding: The Theragnostic Promise of Conjugated Peptides – Giuseppe Pappalardo, CNR-IC Catania

15:45 – 16:00 – Crosslinking MS, coFractionation MS and deep learning to define in situ protein-protein interactions – Andrea Graziadei, Human Technopole Milan(Selected oral contribution)

16:00 – 16:15 – An integrative structural biology study of the RAD51–BRC repeats interplay in Homologous Recombination – Francesco Rinaldi, Italian Institute of Technology(Selected oral contribution)

16:15 – 16:35 – Coffee break

Afternoon session 2

Chair: Laura Siracusa

16:35 – 17:05 – (Keynote) Mass spectrometry-based proteomics and metabolomics unveil metabolic vulnerabilities in cancer cell – Angela Bachi, IFOM

17:05 – 17:35 – (Keynote) Misfolding and aggregation in neurodegenerative diseases: role of non-covalent interactions – Luigi Russo, University of Campania “Luigi Vanvitelli”

17:35 – 18:05 – MALDI and ESI MS to map glycoconjugate complexity – Angelo Palmigiano, CNR-IPCB Catania

18:05 – 18:25 – From structure to immunity: mass spectrometry-driven characterization of lipopolysaccharides – Marcello Mercogliano, University of Naples Federico II(Selected oral contribution)

18:20 – 18:35 – AuNCs-SG Nanosystem a potential tool for enhanced IL6 Sensing -Ester Butera, University of Catania(Selected oral contribution)

 

Morning session

09:00 – 13:30 – ITACA.SB Social activity

13:30 – 14:30 – Lunch

Afternoon session 1

Chair: Nicola D’Antona

14:30 – 15:00 – (Keynote) High sensitivity optical nanosensing for liquid biopsy – Francesco Saverio Pavone, University of Florence, LENS

15:00 – 15:30 – Engineering Macrocycles for Next-Generation Drug Discovery and Delivery – Grazia Maria Letizia Consoli, CNR-ICB Catania

15:30 – 15:45 – From Phenotype to Mechanism: Computational Target Deconvolution in Cancer TherapeuticsVenera Russo, Dream Factory Lab, Vera Salus Ricerca S.r.l., J4Med Lab(Selected oral contribution)

15:45 – 16:00 – Calixarene-Based Micelles Co-Loaded with Ciprofloxacin and Curcumin and their Incorporation into Poly(vinyl alcohol) Film Blends for Local Multidrug Treatment of Infections – Lucia Cambria, Università di Messina – (Selected oral contribution)

16:00 – 16:15 – Stimuli-responsive assemblies for targeted drug delivery: from molecular interactions to functional nanocarriers – Giuseppina Domenica Giovanna Santonoceta, University of Catania(Selected oral contribution)

16:15 – 16:35 – Coffee break

Afternoon session 2

Chair: Giuseppe Pappalardo

16:35 – 17:05 – (Keynote) From molecular design to structural insight: imidazole heterocycles in cancer research – Prasanna Ramani, Amrita Vishwa Vidyapeetham

17:05 – 17:35 – Ethanolamides analogues as internal standards for quantitative ecb analysis: lipase-mediated synthesis and method evaluation – Laura Siracusa, CNR-ICB Catania

17:35 – 17:50 – Cyclodextrins as Drug Delivery Systems – Claudia Giovanna Leotta, Dream Factory Lab, Vera Salus Ricerca S.r.l., J4Med Lab – (Selected oral contribution)

17:50 – 18:05 – Non enzymatic strategies for Phe and Tyr detection – Giorgia Fangano, University of Catania – (Selected oral contribution)

20:30 – Social dinner

 

Morning session 1 

Chair: Sabrina Carroccio

09:00 – 09:30 – (Keynote) Non-invasive multispectral optical sensing for real time detection of psychological stress on skin – Victoria Barygina, University of Florence, LENS

09:30 – 10:00 – High-Resolution Tandem Mass Spectrometry as powerful tool for the identification and quantification of emerging contaminants in complex matrices – Valentina Giglio, CNR-IPCB Catania

10:00 – 10:30 – Bioactive phytocomplexes from the aromatic plant supply chain: from essential oils to hydrolates and distillation by-products – Marco Edoardo Napoli, CNR-ICB Catania

10:30 – 10:45 – Integrating GC-HRMS and GC×GC-HRMS to Investigate Relevant Skin Volatiles in Mother-Newborn Communication – Serena Reale, University of Pisa(Selected oral contribution)

10:45 – 11:00 – Linking Biofilm-Forming Antarctic Bacteria, Functional Materials, and Quantitative Mass Spectrometry for Bioremediation Applications – Andrea Cattaneo, University of Venice Ca’ Foscari(Selected oral contribution)

11:00 – 11:25 – Coffee break

Morning session 2

Chair: Angelo Palmigiano

11:25 – 11:55 – (Keynote) From Mass to Structure: 3D Imaging of Macromolecular Complexes and Hybrid Nanomaterials Using a Multipurpose TEM – Roberto Marotta, Italian Institute of Technology

11:55 – 12:25 – MS-based approaches for the characterization of chickpea seed proteins – Vincenzo Cunsolo, University of Catania

12:25 – 12:55 – Unraveling Amyloid Peptide Aggregation and Metal ion Interactions: Insights from Mass Spectrometry – Giuseppe Di Natale, CNR-IC Catania

12:55 – 13:10 – Palladium-Catalyzed C-H Activation: A Versatile Gateway to Biologically Active Fused 1,2,3-Triazole (Dihydro)quinolines – Dario Allevi, Polytechnic University of Milan(Selected oral contribution)

13:10 – 13:20 – Closing Remarks – Michele Saviano, Scientific Coordinator of ITACA.SB

13:20 – 14:30 – Lunch

14:30 – Departures

Organizers

Sabrina Carroccio

CNR-IPCB Catania

Nicola D’Antona

CNR-ICB Catania

Danilo Milardi

CNR-IC Catania

Angelo Palmigiano

CNR-IPCB Catania

Giuseppe Pappalardo

CNR-IC Catania

Laura Siracusa

CNR-ICB Catania

Questions? Contact us